Balancing Women’s Hormones Naturally

The Vital Role of DHEA in Estrogen, Progesterone, and Testosterone Support

Hormones are the silent orchestrators of a woman’s overall well-being, influencing everything from mood and metabolism to reproductive health and cognitive function. Among the lesser-discussed yet critically important hormones is DHEA (dehydroepiandrosterone)—a precursor to major sex hormones like estrogen, progesterone, and testosterone. Produced primarily in the adrenal glands and in smaller amounts by the ovaries, DHEA levels peak in early adulthood and naturally decline with age, stress, and chronic illness. This decline can significantly affect hormone balance, energy, mood, and sexual health in women.

Understanding DHEA and Its Role in Female Hormone Balance

DHEA is the “parent hormone” that gives rise to estrogen and testosterone, both vital for menstrual health, bone density, mood regulation, libido, and cardiovascular health. It also influences progesterone levels indirectly by supporting overall adrenal hormone balance. Research has shown that low DHEA levels are linked to symptoms of adrenal fatigue, mood disorders, decreased libido, and cognitive decline in women, particularly during perimenopause and menopause [1].

Symptoms of Hormonal Imbalance: Androgens Too High or Too Low

Androgens, including testosterone and DHEA, must be carefully balanced in women—too little or too much can both lead to unpleasant symptoms.

Signs of Low Androgens in Women:

• Low libido and vaginal dryness

• Fatigue and poor stress tolerance

• Muscle weakness or loss of muscle mass

• Depression, anxiety, or mood swings

• Poor memory and cognitive decline

• Thin or fragile skin

Signs of High Androgens in Women:

• Acne and oily skin

• Hirsutism (excessive facial/body hair)

• Irregular menstrual cycles

• Thinning scalp hair (female-pattern hair loss)

• Polycystic ovary syndrome (PCOS) symptoms

• Insulin resistance or weight gain around the abdomen

[2] Women with PCOS often exhibit higher levels of circulating androgens like testosterone and DHEA-S, contributing to metabolic and reproductive dysfunction [3].

Natural and Holistic Approaches to Supporting DHEA and Hormone Balance

Rather than resorting to hormone replacement therapy (HRT) in every case, a holistic approach using herbs, nutrition, and lifestyle can safely and effectively support the body's own hormone production.

1. Herbal Allies for Androgen and Hormonal Support

• Maca (Lepidium meyenii): Known as an adaptogen, maca helps regulate the HPA axis and supports healthy DHEA levels. It has been shown to improve mood, libido, and hormone balance in perimenopausal women [4].

• Ashwagandha (Withania somnifera): A renowned adaptogen, ashwagandha supports adrenal health and has been shown to raise DHEA levels in women with adrenal insufficiency [5].

• Tribulus terrestris: Traditionally used to enhance libido and fertility, Tribulus has been found to increase testosterone in women with sexual dysfunction [6].

• Vitex (Chaste Tree Berry): Vitex helps regulate the menstrual cycle by influencing prolactin and progesterone production, indirectly supporting balanced androgens.

• Licorice Root (Glycyrrhiza glabra): While controversial in large amounts due to potential cortisol elevation, licorice in moderation can modulate androgen levels and support adrenal function [7].

2. Nutritional Support for Healthy DHEA and Hormones

• Zinc: This mineral is crucial for androgen production and function. Zinc deficiency has been linked to lower testosterone levels in both men and women.

• Healthy Fats: Cholesterol is the precursor for all steroid hormones including DHEA, estrogen, and progesterone. Diets rich in omega-3s, avocados, coconut oil, and nuts support hormone synthesis.

• Vitamin D3: Plays a vital role in sex hormone production. Deficiency has been associated with lower levels of estrogen and testosterone.

• B Vitamins (especially B5 and B6): These are essential for adrenal function and hormone synthesis.

• Magnesium: Supports adrenal and thyroid function and is a cofactor in over 300 enzymatic processes including hormone production.

3. Lifestyle Foundations for Hormonal Harmony

• Stress Reduction: Chronic stress suppresses DHEA production by overstimulating cortisol. Incorporating mindfulness, yoga, breathing exercises, or nature walks can support adrenal recovery.

• Resistance Training: Strength training helps boost natural testosterone and DHEA levels, supports bone density, and enhances metabolism.

• Sleep: Prioritizing 7–9 hours of restorative sleep helps regulate the HPA axis and hormone rhythms.

Citations

1. Labrie, F., et al. (2009). DHEA and its conversion into androgens and estrogens in peripheral target tissues: intracrinology. Frontiers in Neuroendocrinology, 30(3), 288–312. https://doi.org/10.1016/j.yfrne.2009.04.001

2. Davison, S. L., et al. (2005). Androgens and women: current controversies and future directions. The Journal of Clinical Endocrinology & Metabolism, 90(8), 5106–5111. https://doi.org/10.1210/jc.2005-0505

3. Azziz, R., et al. (2004). The androgen excess and PCOS society criteria for the polycystic ovary syndrome: the complete task force report. Fertility and Sterility, 91(2), 456–488. https://doi.org/10.1016/j.fertnstert.2008.06.035

4. Meissner, H. O., et al. (2006). Hormone-balancing effect of pre-gelatinized organic Maca (Lepidium peruvianum Chacon): (II) Physiological and symptomatic responses of early-postmenopausal women to Maca in double-blind, randomized, placebo-controlled, multi-centre clinical study. International Journal of Biomedical Science, 2(4), 360–374.

5. Chandrasekhar, K., et al. (2012). A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of Ashwagandha root in reducing stress and anxiety. Indian Journal of Psychological Medicine, 34(3), 255–262.

6. Gallo, M., et al. (2018). Efficacy of Tribulus terrestris for the treatment of hypoactive sexual desire disorder in women: a randomized, double-blind, placebo-controlled study. Gynecological Endocrinology, 34(8), 646–650.

7. Armanini, D., et al. (2004). Licorice reduces serum testosterone in healthy women. Steroids, 69(11–12), 763–766. https://doi.org/10.1016/j.steroids.2004.06.006